Laugh linesWe wouldn’t trade a few decades’ worth of laughs for anything. But the lines they leave around the mouth—said to resemble parentheses—are another story. A derm-administered hyaluronic acid filler can even them out. Belotero Balance ($750 and up for a syringe; belotero.com), approved by the FDA in 2011, is denser than other fillers, so it’s less likely to cause bluish discoloration below the skin, an occasional side effect. (Results last 3 to 6 months.) At home, a cream with retinol can make wrinkles look fainter. Dr. Wexler’s pick: RoC Retinol Correxion Deep Wrinkle Filler ($23; rocskincare.com).PuckeringVertical lines above and below the lips are caused by collagen loss due to sun exposure and repeated puckering (talking, drinking, and smoking). The most effective treatment: a Fraxel repair laser ($1,000-plus per session; requires three to five visits, on average) to promote collagen growth. Or try StriVectin-SD Power Serum for Wrinkles ($99; strivectin.com), which has peptides that make skin look firmer, plus a form of niacin that restores the skin’s barrier and protects against further damage. Thinning lipsDaily exfoliation stimulates blood flow and eliminates dead skin cells, making lips look brighter and fuller. Skip the age-old toothbrush trick (bristles can tear skin) and instead use a lip-specific exfoliator, such as Fresh Sugar Lip Polish ($22.50; sephora.com). For instant volume, try a plumping lip gloss, like Clinique Full Potential Lips Plump and Shine ($17.50; clinique.com). And don’t fear injections; done correctly, they can add welcome body to thinning lips. Just ask your dermatologist to fill the top lip less than the bottom one, Dr. Wexler advises, to avoid the Daffy Duck look. (Get 5 more ways to plump thin lips.) More from Prevention:How To Prevent Wrinkles